15pastures
more than 100 acres
plus 15K sq ft. large animal handling
Bethyl
Laboratories
Bethyl Laboratories began as a family-owned company in Montgomery, Texas, earning a reputation for rigorous antibody validation that set the standard for the industry. Since joining Fortis Life Sciences in 2020, Bethyl has continued those same validation practices while expanding its Farm-to-Bench™ capabilities and providing customers with access to the specialized expertise of six complementary life science companies.
Bethyl By the Numbers
8ponds
8 man-made hydration and enrichment ponds with connected plumbing
Automatic solar-powered feeders
and fresh waters in every pasture and barn
11systems
11 veterinary plasmapheresis collection systems
On-site backup generator
and temperature-controlled animal facilities
50,000sq ft
50,000 square feet of climate-controlled housing
45,000 sq ft of lab space
Western blotting, in-house custom-column antibody purification, cell sorting, phage display, and custom spatial biology/IHC panel design.
4°C/-20°C/-80°C
Cold storage at 4°C, -20°C, -80°C, and liquid nitrogen
Six-Pillar Validation
Identifying the intended target is only the first requirement. An antibody also has to show high sensitivity with minimal cross-reactivity. Bethyl tests specificity against paired antibodies raised to distinct epitopes on the same protein, rather than trusting a single antibody's result.
Specificity has to hold in immunoprecipitation or Western blot before an antibody moves on to testing in immunohistochemistry, immunocytochemistry, ChIP, or proximity ligation assay.
Bethyl serves to advance science by developing highly-qualified antibodies, including many to emerging and underserved protein targets.
Custom Antibody
Services
Bethyl built custom antibody programs for decades, complete packages spanning peptide synthesis through affinity purification against an antigen-specific immunosorbent.
All ServicesCustom Antibody Development & Manufacturing
Monoclonal, polyclonal, and recombinant antibody programs, from immunization through scale-up and bulk supply.
See Custom Antibody DevelopmentCustom VHH Antibody Discovery
Membrane proteins, ion channels, and other structurally difficult epitopes often call for a different discovery method: VHH single-domain antibodies.
See VHH Discovery ServiceCustom Spatial Biology & Multiplex IHC Solutions
Custom multiplex IHC panel design and spatial biology services, from tissue processing through multiplex imaging
See Spatial Biology ServicesCustom Antibody Conjugation
Fluorophore and enzyme conjugates, including HRP and AP, prepared for IHC, ELISA, and Western blot.
See Conjugation Services
Antibody Manufacturing You Can Trust
Bethyl manufactures and validates every antibody in-house at its Montgomery, Texas facility, spanning veterinary care, development, production, and validation in one integrated system.
Download the Six-Pillar Validation WhitepaperBethyl now operates as one of six Fortis manufacturing and R&D sites.
See Certifications
Registration & Assurance
As a USDA-registered research facility, Bethyl adheres to the Animal Welfare Act in the care of the animals behind every antibody it produces.
USDA Class R Research Facility Registration #74-R-0044
PHS/NIH/OLAW Animal Welfare #A3991-01
