Goat anti-Chk1 Antibody Affinity Purified
Catalog #
Chk1
Human
WB
Goat
Polyclonal
Whole IgG
Between 200 and 250
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Rat
Rat
Human
2 - 8 °C
1 year from date of receipt
USA
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.
Alternate Names
cell cycle checkpoint kinase; Checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHK1; CHK1 checkpoint homolog; Chk1-S; serine/threonine-protein kinase Chk1
Applications