Rabbit anti-eIF3K/EIF3S12 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Eukaryotic initiation factor 3 subunit K (eIf3K) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3 has been found to localize to both the nucleus and cytoplasm. In the cytoplasm, eIf3K associates with keratin 18 in intermediate filaments of epithelial cells and may have an apoptosis-promoting function. It also has been shown to interact with cyclin D3.
Alternate Names
ARG134; eIF-3 p25; eIF-3 p28; eIF3k; EIF3-p28; EIF3S12; Eukaryotic translation initiation factor 3 subunit 12; eukaryotic translation initiation factor 3 subunit K; eukaryotic translation initiation factor 3, subunit 12; HSPC029; M9; MSTP001; muscle specific; muscle-specific gene M9 protein; PLAC24; PLAC-24; PRO1474; PTD001
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.