Rabbit anti-Cul4B Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-864A maps to a region between residue 863 and 913 of human Cullin 4B using the numbering given in entry NP_003579.3 (GeneID 8450).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to Cul4B immobilized on solid support.
The epitope recognized by A303-864A-T maps to a region between residue 863 and 913 of human Cullin 4B using the numbering given in entry NP_003579.3 (GeneID 8450).
Additional Product Information
Cullin-4B is a member of the cullin family. Cullin-4B forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. Cullin-4B interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E [taken from NCBI Entrez Gene (Gene ID: 8450)].
Alternate Names
CUL-4B; cullin-4B; MRXHF2; MRXS15; MRXSC; SFM2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).