Rabbit anti-FDPS Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A305-045A maps to a region between residue 50 to 100 of human Farnesyl pyrophosphate synthase using the numbering given in entry P14324.4 (GeneID 2224).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to FDPS immobilized on solid support.
The epitope recognized by A305-045A-T maps to a region between residue 50 to 100 of human Farnesyl pyrophosphate synthase using the numbering given in entry P14324.4 (GeneID 2224).
Additional Product Information
Farnesyl diphosphate synthase (FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P14324].
Alternate Names
(2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; FPP synthase; FPP synthetase; FPPS; FPS; Geranyltranstransferase; POROK9
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.