Purified Recombinant SARS-CoV-2-S-RBD/HIS Tag Protein [HEK293 Expressed]
Product Details
Specifications
Protein was purified from cell culture supernatant by IMAC chromatography.
30-35kDa observed molecular weight by SDS-PAGE under reducing conditions.
Purity >90% by SDS-PAGE.
SARS-CoV-2-S-RBD protein binding activity determined in functional ELISA with ACE2/Rb-Fc (Cat# P710-001). See figure for details.
Additional Product Information
The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and mediates attachment of the virus particle and entry into the host cell though an interaction with the virla receptor binding domain (RBD) and ACE2. The spike protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests. (NCBI)
Alternate Names
spike glycoprotein