/ Antibodies & Antisera / p53 Pathway Antibodies / Rabbit anti-Chk2 IHC Antibody
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p53 Pathway Antibodies  

Rabbit anti-Chk2 IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
Chk2
Reactivity:
Human
Applications:
IHC
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 493 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

$121.00 $459.00
Qty:
Bulk Request

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
500 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Request Formulation Change
Country of Origin
USA

Additional Product Information

Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are RAD53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, Brca1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, RAD53, HuCds1, and PP1425.

11200
CHEK2
checkpoint kinase 2
O96017
Serine/threonine-protein kinase Chk2

Alternate Names

CDS1; cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; CHK2; CHK2 checkpoint homolog; hCds1; HuCds1; LFS2; PP1425; RAD53; serine/threonine-protein kinase Chk2

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.