Rabbit anti-ALMS1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A301-816A-T maps to a region between residue 3400 and 3450 of human Alstrom syndrome 1 using the numbering given in entry EAW99731.1 (GeneID 7840).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to ALMS1 immobilized on solid support.
The epitope recognized by A301-816A maps to a region between residue 3400 and 3450 of human Alstrom syndrome 1 using the numbering given in entry EAW99731.1 (GeneID 7840).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Mutations in the ALMS1 gene are the cause of Alstrom syndrome, a rare autosomal recessive disease characterized by type 2 diabetes mellitus, obesity, cardiomyopathy, and neurosensory defects such as cone-rod retinal dystrophy, and hearing loss. In the cell, ALMS1 localizes to basal bodies of ciliated cells and centrosomes and is thus a member of proteins associated with genetic ciliopathies.
Alternate Names
ALSS; Alstrom syndrome 1; Alstrom syndrome protein 1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.