Rabbit anti-ATX2/SCA2 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A301-118A maps to a region between residue 1262 and 1312 of human ataxin 2 (spinocerebellar ataxia 2) using the numbering given in entry NP_002964.2 (GeneID 6311).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to ATX2/SCA2 immobilized on solid support.
The epitope recognized by A301-118A-T maps to a region between residue 1262 and 1312 of human ataxin 2 (spinocerebellar ataxia 2) using the numbering given in entry NP_002964.2 (GeneID 6311).
Additional Product Information
Pentanucleotide repeat expansions in the ATX2/SCA2 gene have been linked to spinocerebellar ataxia, a disorder that is characterized by gait ataxia, cognitive development, and seizures. The function of the ATX2/SCA2 has not been determined.
Alternate Names
ataxin-2; ATX2; SCA2; spinocerebellar ataxia type 2 protein; TNRC13; trinucleotide repeat-containing gene 13 protein
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.