Rabbit anti-BAT3 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A302-038A maps to a region between residue 200 and 250 of human HLA-B associated transcript 3 using the numbering given in entry NP_004630.3 (GeneID 7917).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to BAT3 immobilized on solid support.
The epitope recognized by A302-038A-T maps to a region between residue 200 and 250 of human HLA-B associated transcript 3 using the numbering given in entry NP_004630.3 (GeneID 7917).
Additional Product Information
HLA-B-associated transcript 3 was originally identified as a gene within the class III region of the major histocompatibility complex (MHC). In Xenopus, the homolog of BAT3 is known as Scythe. Scythe has been shown to play a role in the regulation of apoptosis. BAT3 is suggested to play a role in both proliferation and apoptosis, and it is suggested to influence these processes as a co-chaperone recruiter. BAT3 has been shown to be an essential regulator of the DNA damage-induced acetylation of p53 and the p53-mediated response to genotoxic stress.
Alternate Names
BAG family molecular chaperone regulator 6; BAG-6; BAT3; BCL2-associated athanogene 6; D6S52E; G3; HLA-B-associated transcript 3; large proline-rich protein BAG6; large proline-rich protein BAT3; protein G3; protein Scythe; scythe
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.