Rabbit anti-Bcl11a Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A300-382A maps to a region between residue 775 and the C-terminus (residue 835) of human B-cell CLL/Lymphoma 11A using the numbering given in Swiss-Prot entry Q9H165 (GeneID 53335).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Bcl11a is a transcription factor that functions in B cell hematopoiesis and the generation of B lineage progenitors. Bcl11a has been identified as an oncogene involved in lymphoma pathogenesis and may function as a modulator of ARP1 transcriptional repression.
Alternate Names
B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; C2H2-type zinc finger protein; COUP-TF-interacting protein 1; CTIP1; DILOS; ecotropic viral integration site 9 homolog; ecotropic viral integration site 9 protein homolog; EVI9; EVI-9; HBFQTL5; zinc finger protein 856; ZNF856
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.