Rabbit anti-CBX3 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00204 maps to a region between residues 133 and the C-terminus (residue 183) of human chromobox homolog 3 using the numbering given in entry NP_009207.2 (GeneID 11335). Antibody was affinity purified using an epitope specific to CBX3 immobilized on solid support.
The epitope recognized by IHC-00204-T maps to a region between residues 133 and the C-terminus (residue 183) of human chromobox homolog 3 using the numbering given in entry NP_009207.2 (GeneID 11335).
Additional Product Information
CBX3 (chromobox protein homolog 3), also known as HP1gamma (heterochromatin protein 1 homolog gamma), is one of 3 isoforms of HP1 that binds heterochromatin and functions as a structural adaptor to stabilize and organize macromolecular complexes with nucleosomes for higher chromatin structure. All of the HP1 isoforms possess a chromodomain and chromoshadow domain and associate with methylated histones that mediate transcriptional repression.
Alternate Names
chromobox homolog 3 (HP1 gamma homolog, Drosophila); chromobox protein homolog 3; HECH; heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HP1 gamma; HP1 gamma homolog; HP1-GAMMA; HP1Hs-gamma; modifier 2 protein
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.