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Rabbit anti-CD137 Recombinant Monoclonal Antibody [BLR051F]

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
CD137
Reactivity:
Human
Platforms:
PhenoImager™ HT
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR051F
Format:
Whole IgG
Immunogen:
Residues 24-189 (ECD)
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Purified
100 µl (50+ tests)

10 µl (5+ tests)

$127.00 $482.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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Production Procedures
Recombinant antibody was purified from cell culture supernatant.

Immunogen was a recombinant protein representing the extracellular domain of human CD137 (residues 24-189, NP_001552.2).
Country of Origin
USA

Additional Product Information

CD137 is a member of the TNF-receptor superfamily; it is a receptor that contributes to the clonal expansion, survival, and development of T cells. CD137 can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 3604)].

3604
TNFRSF9
TNF receptor superfamily member 9
Q07011
Tumor necrosis factor receptor superfamily member 9

Alternate Names

4-1BB; 4-1BB ligand receptor; CD antigen CD137; CD137; CD137 antigen; CDw137; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; receptor protein 4-1BB; T cell antigen ILA; T-cell antigen 4-1BB homolog; T-cell antigen ILA; tumor necrosis factor receptor superfamily member 9

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.