Rabbit anti-CHD6 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
CHD6 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD6 has been shown to localize to sites of mRNA synthesis and associate with RNA polymerase II suggesting a role in RNA transcription and maturation.
Alternate Names
ATP-dependent helicase CHD6; CHD5; CHD-6; chromodomain-helicase-DNA-binding protein 6; helicase C-terminal domain- and SNF2 N-terminal domain-containing protein; radiation-induced gene B protein; RIGB
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.