Rabbit anti-CKII alpha IHC Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Casein kinase II (CKII) is a serine/threonine protein kinase that is required for progression through the cell cycle but whose major functions are not clearly understood. CKII is composed of a heterotetrameric complex that includes alpha and alpha-prime catalytic subunits and a beta non-catalytic subunit. Although from independent genes, CKII alpha and CKII alpha-prime can compensate for each other for some functions. However in response to ionizing radiation (IR) damage, CKII alpha and CKII alpha-prime appear to function independently in inhibiting apoptosis signaling.
Alternate Names
casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; casein kinase II subunit alpha; CK II alpha; CK2 catalytic subunit alpha; CK2A1; Cka1; Cka2; CKII; OCNDS; protein kinase CK2
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.