Rabbit anti-CoREST Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A300-130A maps to a region between residues 425 and the C-terminus (residue 482) of human REST (RE1-silencing transcription factor) corepressor using the numbering given in entry NP_055971.1 (GeneID 23186)
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to CoREST immobilized on solid support.
The epitope recognized by A300-130A-T maps to a region between residues 425 and the C-terminus (residue 482) of human REST (RE1-silencing transcription factor) corepressor using the numbering given in entry NP_055971.1 (GeneID 23186).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
CoREST has been identified as a component of a histone deacetylase (HDAC) complex as well as an interacting protein and corepressor of the REST (repressor element 1 silencing transcription factor) transcription factor. HDAC complexes deacetylate chromatin to repress transcription and silence genes. The CoREST complex may be important in restricting gene expression in a tissue-specific manner.
Alternate Names
COREST; Protein CoREST; RCOR; REST corepressor 1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).