Rabbit anti-CPSF68 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00267 maps to a region between residue 501 and 551 of human cleavage and polyadenylation specific factor 6, 68kDa using the numbering given in entry NP_008938.1 (GeneID 11052).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to CPSF68 immobilized on solid support.
The epitope recognized by IHC-00267-T maps to a region between residue 501 and 551 of human cleavage and polyadenylation specific factor 6, 68kDa using the numbering given in entry NP_008938.1 (GeneID 11052).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Cleavage and polyadenylation specific factor 68 (CPSF68) is the 68 kDa subunit of the cleavage factor Im complex (CFIm). The CFIm is a heterodimer composed of a 25 kDa (CPSF5) subunit and either the 59 kDa (CPSF7) or 68 kDa (CPSF6) subunit and is essential to the first step of pre-mRNA 3’-end processing. CPSF68 bears an N-terminal RNA- recognition motif (RRM) that is necessary for binding CPS5.
Alternate Names
CFIM; CFIM68; CFIM72; cleavage and polyadenylation specific factor 6, 68kDa; cleavage and polyadenylation specificity factor 68 kDa subunit; cleavage and polyadenylation specificity factor subunit 6; cleavage factor Im complex 68 kDa subunit; CPSF 68 kDa subunit; HPBRII-4; HPBRII-7; pre-mRNA cleavage factor I, 68kD subunit; pre-mRNA cleavage factor Im (68kD); pre-mRNA cleavage factor Im 68 kDa subunit; protein HPBRII-4/7
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.