Rabbit anti-DIS3 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-765A maps to a region between residue 858 and 908 of human DIS3 mitotic control homolog using the numbering given in entry NP_055768.3 (GeneID 22894).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to DIS3 immobilized on solid support.
The epitope recognized by A303-765A-T maps to a region between residue 858 and 908 of human DIS3 mitotic control homolog using the numbering given in entry NP_055768.3 (GeneID 22894).
Additional Product Information
DIS3 mitotic control homolog is a putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BX67].
Alternate Names
2810028N01Rik; DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 mitotic control homolog; dis3p; EXOSC11; exosome complex exonuclease RRP44; exosome component 11; KIAA1008; mitotic control protein dis3 homolog; Protein DIS3 homolog; ribosomal RNA-processing protein 44; RRP44
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.