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Primary Antibodies

Rabbit anti-DTL/CDT2 Antibody Affinity Purified

Name: Rabbit anti-DTL/CDT2 Antibody
Brand: Bethyl Laboratories
SKU: A300-947A
Price: 121 USD

Bethyl Laboratories Catalog #

Citations (2)

Target:

DTL/CDT2

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 375 and 425

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$121.00 $433.00

Qty:

Product Details

Specifications

Verified Reactivity

Human

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Country of Origin

USA

Additional Product Information

DTL/CDT2 is a component of the CUL4A-DDB1 E3 ubiquitinating complex and plays a role in downregulating CDT1, an essential component of pre-replication complexes (Pre-RC) that ensures the genome is replicated only once per cycle. As part of the CUL4A-DDB1 E3 ligase complex DTL/CDT2 is also involved in the regulation of other proteins involved in the G2/M cell cycle checkpoint.

Gene ID: 51514

Gene Symbol: DTL

Gene Name: denticleless E3 ubiquitin protein ligase homolog

Uniprot ID: Q9NZJ0

Protein Name: Denticleless protein homolog

Alternate Names

CDT2; DCAF2; DDB1- and CUL4-associated factor 2; denticleless protein homolog; L2DTL; lethal(2) denticleless protein homolog; RAMP; RA-regulated nuclear matrix-associated protein; retinoic acid-regulated nuclear matrix-associated protein

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.