Rabbit anti-EFTUD2/SNRP116 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00161 maps to a region between residues 1 and 50 of human Elongation Factor Tu GTP Binding Domain Containing 2 (U5 snRNP-Specific Protein, 116 kD ) using the numbering given in entry NP_004238.2 (GeneID 9343). Antibody was affinity purified using an epitope specific to EFTUD2/SNRP116 immobilized on solid support.
The epitope recognized by IHC-00161-T maps to a region between residues 1 and 50 of human Elongation Factor Tu GTP Binding Domain Containing 2 (U5 snRNP-Specific Protein, 116 kD ) using the numbering given in entry NP_004238.2 (GeneID 9343).
Additional Product Information
The splicesome is the molecular machine responsible for catalyzing intron removal from pre-mRNA transcripts. The splicesome is composed of several small nuclear RNAs (snRNAs) complexed with their associated proteins [together termed snRNPs (small nuclear ribonucleoprotein)]. One of the major classes of snRNPs includes the U1, U2, U4, U5 and U6 snRNP. EFTUD2/SNRP116 is a component of the U5 snRNP. EFTUD2/SNRP116 is a GTPase that may play a role in disrupting U4/U6 helices prior to splicesome activation.
Alternate Names
116 kDa U5 small nuclear ribonucleoprotein component; elongation factor Tu GTP-binding domain-containing protein 2; hSNU114; MFDGA; MFDM; SNRNP116; Snrp116; Snu114; SNU114 homolog; U5 snRNP-specific protein, 116 kDa; U5-116 kDa; U5-116KD
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.