Rabbit anti-FOP Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
FOP (FGFR1 Oncogene Partner) was identified and cloned as part of a translocation breakpoint in which the protein kinase domain of the FGFR1 (Fibroblast Growth Factor Receptor 1) gene is fused to the leucine-rich domain of FOP. Translocations involving FOP and FGFR1 are associated with stem cell myeloproliferative disorder (MPD). FOP has also been identified as a part of a centrosomal complex and has been shown to be required for the anchoring and organization of the microtubule network to subcellular structures.
Alternate Names
FGFR1 oncogene partner; fibroblast growth factor receptor 1 oncogene partner; FOP
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.