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Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
Granzyme B
Reactivity:
Human
Platforms:
COMET™, PhenoImager™ HT
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR022E
Format:
Whole IgG
Immunogen:
Residues 19-247 (mature protein)
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Purified
100 µl (50+ tests)

10 µl (5+ tests)

100 µg (BSA-Free)

$127.00 $794.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
50 µg/ml 1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Request Formulation Change Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Request Formulation Change
Production Procedures
The monoclonal antibody was purified from cell culture supernatant.

Immunogen was a recombinant protein representing human Granzyme B (residues 19-247, NP_004122.2).
The monoclonal antibody was purified from cell culture supernatant.
Immunogen was a recombinant protein representing human Granzyme B (residues 19-247, NP_004122.2).
Country of Origin
USA

Additional Product Information

Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]

3002
GZMB
granzyme B
P10144
Granzyme B

Alternate Names

C11; cathepsin G-like 1; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTLA-1; CTSGL1; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; fragmentin 2; Fragmentin-2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme-2; HLP; human lymphocyte protein; Lymphocyte protease; SECT; T-cell serine protease 1-3E

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).