Rabbit anti-HRS Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A300-988A-T maps to a region between residue 350 and 400 of human growth factor-regulated tyrosine kinase substrate using the numbering given in entry NP_004703.1 (GeneID 9146).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to HRS immobilized on solid support.
The epitope recognized by A300-988A maps to a region between residue 350 and 400 of human growth factor-regulated tyrosine kinase substrate using the numbering given in entry NP_004703.1 (GeneID 9146).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) is an endosomal protein that participates in the trafficking and sorting of proteins to degradative or recycling pathways. HRS can bind ubiquitin directly and plays a key role in sorting ubiquitinated proteins to lysosomes. HRS has also been demonstrated to regulate protein sorting independent of its ubiquitin-binding motif.
Alternate Names
hepatocyte growth factor-regulated tyrosine kinase substrate; HRS; human growth factor-regulated tyrosine kinase substrate; protein pp110
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.