Rabbit anti-INF2 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-428A maps to a region between residue 950 and 1000 of human Inverted Formin-2 using the numbering given in entry NP_071934.3 (GeneID 64423).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to INF2 immobilized on solid support.
The epitope recognized by A303-428A-T maps to a region between residue 950 and 1000 of human Inverted Formin-2 using the numbering given in entry NP_071934.3 (GeneID 64423).
Additional Product Information
Inverted formin-2 (INF2) is a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that human INF2 may function in polymerization and depolymerization of actin filaments. Mutations in the INF2 gene have been associated with focal segmental glomerulosclerosis 5 [taken from NCBI Entrez Gene (Gene ID: 64423)].
Alternate Names
C14orf151; C14orf173; CMTDIE; FSGS5; HBEAG-binding protein 2 binding protein C; HBEBP2-binding protein C; inverted formin-2; pp9484
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.