Rabbit anti-Interferon alpha/ beta receptor 1 Recombinant Monoclonal Antibody [BLR265L]
Product Details
Specifications
Request Formulation Change Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Request Formulation Change
Immunogen was a recombinant protein representing the extracellular domain of human Interferon alpha/ beta receptor 1 (residues 27-436, NP_000620.2).
Additional Product Information
Interferon alpha/beta receptor 1 (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P17181].
Alternate Names
alpha-type antiviral protein; AVP; beta-type antiviral protein; CRF2-1; cytokine receptor class-II member 1; cytokine receptor family 2 member 1; IFN-alpha/beta receptor 1; IFN-alpha-REC; IFNAR; IFNBR; IFN-R-1; IFRC; interferon (alpha, beta and omega) receptor 1; interferon alpha/beta receptor 1; interferon receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.