Rabbit anti-K-Ras Recombinant Monoclonal Antibody [BLR321M]

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

K-Ras

Reactivity:

Human

,

Mouse

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR321M

Format:

Whole IgG

Immunogen:

between 50 and 100

Isotype:

IgG

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

$127.00 $482.00
Qty:

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free


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Production Procedures

Recombinant antibody was purified from cell culture supernatant.

Immunogen was a peptide representing a region between residue 50 and 100 of human GTPase K-Ras using the numbering given in entry NP_004976.2 (Gene ID 3845).

Additional Product Information

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. K-ras plays an important role in the regulation of cell proliferation and plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P01116].

3845

KRAS

KRAS proto-oncogene, GTPase

P01116

GTPase KRas

Alternate Names

cellular c-Ki-ras2 proto-oncogene;cellular transforming proto-oncogene;CFC2;c-Ki-ras;c-Ki-ras2;c-Kirsten-ras protein;C-K-RAS;GTPase KRas;KI-RAS;Kirsten rat sarcoma viral oncogene homolog;Kirsten rat sarcoma viral proto-oncogene;K-Ras;K-Ras 2;K-ras p21 protein;KRAS1;KRAS2;K-RAS2A;K-RAS2B;K-RAS4A;K-RAS4B;NS;NS3;oncogene KRAS2;PR310 c-K-ras oncogene;RALD;RASK2;transforming protein p21;v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.


Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).