Rabbit anti-KIF20A/RAB6KIFL Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF20A/RAB6KIFL plays a role in transport within the golgi via interaction with Rab6 small GTPase as well as in mitosis and cytokinesis where it localizes to the spindle in anaphase and cleavage furrow and midbody in telophase.
Alternate Names
GG10_2; kinesin-like protein KIF20A; mitotic kinesin-like protein 2; MKLP2; RAB6 interacting, kinesin-like (rabkinesin6); rab6-interacting kinesin-like protein; RAB6KIFL; rabkinesin-6
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.