Rabbit anti-LEMD3/MAN1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A305-251A maps to a region between residue 300 to 350 of human Inner nuclear membrane protein Man1 using the numbering given in entry Q9Y2U8.2 (GeneID 23592).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to LEMD3/MAN1 immobilized on solid support.
The epitope recognized by A305-251A-T maps to a region between residue 300 to 350 of human Inner nuclear membrane protein Man1 using the numbering given in entry Q9Y2U8.2 (GeneID 23592).
Additional Product Information
LEM domain-containing protein 3 (LEMD3) can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. LEMD3 antagonizes TGF-beta-induced cell proliferation arrest [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y2U8].
Alternate Names
inner nuclear membrane protein Man1; integral inner nuclear membrane protein; LEM domain-containing protein 3; LEMD3/MKX fusion; MAN1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).