Rabbit anti-LMTK2 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Lemur tyrosine kinase (LMTK2) belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. LMTK2 interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. LMTK2 is involved in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggest an essential role of this protein in spermatogeness [taken from NCBI Entrez Gene (Gene ID: 22853)].
Alternate Names
AATYK2; apoptosis-associated tyrosine kinase 2; brain-enriched kinase; BREK; CDK5/p35-regulated kinase; cprk; cyclin-dependent kinase 5/p35-regulated kinase; hBREK; kinase/phosphatase/inhibitor 2; KPI2; KPI-2; Lemur tyrosine kinase 2; LMR2; PPP1R100; protein phosphatase 1, regulatory subunit 100; serine/threonine-protein kinase KPI-2; serine/threonine-protein kinase LMTK2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).