Rabbit anti-MADD IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00621 maps to a region between residue 1597 and 1647 of human MAP-kinase activating death domain using the numbering given in entry NP_003673.3 (GeneID 8567).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to MADD immobilized on solid support.
The epitope recognized by IHC-00621-T maps to a region between residue 1597 and 1647 of human MAP-kinase activating death domain using the numbering given in entry NP_003673.3 (GeneID 8567).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
MAP kinase-activating death domain protein (MADD) is a death domain containing protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activate protein kinase (MAPK) and transduce apoptotic signals. MADD is a multi-pass membrane protein that exists as multiple alternatively spliced forms.
Alternate Names
DENN; differentially expressed in normal and neoplastic cells; IG20; insulinoma glucagonoma clone 20; MAP kinase-activating death domain protein; Rab3 GDP/GTP exchange factor; RAB3GEP
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.