Rabbit anti-MCT8 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A304-351A maps to a region between residue 250 to 300 of human Monocarboxylate Transporter 8 using the numbering given in entry NP_006508.2 (GeneID 6567).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to MCT8 immobilized on solid support.
The epitope recognized by A304-351A-T maps to a region between residue 250 to 300 of human Monocarboxylate Transporter 8 using the numbering given in entry NP_006508.2 (GeneID 6567).
Additional Product Information
Monocarboxylate transporter 8 (MCT8) is a very active and specific thyroid hormone transporter. It stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. It does not transport Leu, Phe, Trp or Tyr (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P36021].
Alternate Names
AHDS; DXS128; DXS128E; MCT 7; MCT 8; MCT7; MCT8; monocarboxylate transporter 7; monocarboxylate transporter 8; MRX22; Solute carrier family 16 member 2; solute carrier family 16, member 2 (thyroid hormone transporter); X-linked PEST-containing transporter; XPCT
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.