Rabbit anti-MEF2C Recombinant Monoclonal Antibody [BLR327M]
Product Details
Specifications
Immunogen was a peptide representing a region between residue 425 and 475 of human Myocyte-specific enhancer factor 2C using the numbering given in entry NP_002388.2 (Gene ID 4208).
Additional Product Information
MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It also plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. MEF2C is crucial for normal neuronal development, distribution, and electrical activity in the neocortex. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q06413].
Alternate Names
C5DELq14.3;DEL5q14.3;MADS box transcription enhancer factor 2, polypeptide C;Myocyte enhancer factor 2C;myocyte-specific enhancer factor 2C
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (A120-113P) with 5% Normal Pig Serum (S100-020) added to the blocking buffer.