Rabbit anti-NEDD-9/CASL/HEF1 Recombinant Monoclonal Antibody [BLR248L]
Product Details
Specifications
Additional Product Information
NEDD-9, aka CASL or HEF1, is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. NEDD-9 is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. [taken from NCBI Entrez Gene (Gene ID: 4739)].
Alternate Names
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; NEDD-9; neural precursor cell expressed developmentally down-regulated protein 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.