Rabbit anti-NFKBIL2 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A303-843A maps to a region between residue 425 and 475 of human Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-cells Inhibitor-like 2 using the numbering given in entry NP_038460.4 (GeneID 4796).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to NFKBIL2 immobilized on solid support.
The epitope recognized by A303-843A-T maps to a region between residue 425 and 475 of human Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-cells Inhibitor-like 2 using the numbering given in entry NP_038460.4 (GeneID 4796).
Additional Product Information
NF-kappa-B inhibitor-like protein 2 (NFKBIL2) is a component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, it may act as a scaffold [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96HA7].
Alternate Names
ikappaBR; I-kappa-B-related protein; IKBR; inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; NFKBIL2; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; tonsoku-like protein
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).