Rabbit anti-OX40/CD134 Recombinant Monoclonal Antibody [BLR314M]
Product Details
Specifications
Immunogen was a recombinant protein representing mouse OX40/CD134 (residues 23-212, NP_035789.1).
Additional Product Information
OX40/CD134 is a member of the TNF-receptor superfamily that has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested OX40/CD134 plays a role in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [taken from NCBI Entrez Gene (Gene ID: 3659)].
Alternate Names
ACT35;CD antigen CD134;CD134;Ly-70;Ox40;OX40 antigen;OX40L receptor;tax-transcriptionally activated glycoprotein 1;tumor necrosis factor receptor superfamily member 4;Txgp1;TXGP1L