Rabbit anti-PC4 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A301-162A maps to a region between residue 77 and 127 of human positive cofactor 4 using the numbering given in entry NP_006704.2 (GeneID 10923).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to PC4 immobilized on solid support.
The epitope recognized by A301-162A-T maps to a region between residue 77 and 127 of human positive cofactor 4 using the numbering given in entry NP_006704.2 (GeneID 10923).
Additional Product Information
PC4 is a multifunctional transcriptional coactivator that plays an important role in transcription, repair, and replication. PC4 interacts with general transcription factors, DNA repair factors, and mRNA processing factors to influence transcription initiation, coactivation, polyadenylation, transcription termination, and transcriptional repression. PC4 has been demonstrated to be a DNA binding protein and a bona fide component of chromatin with chromatin-compacting ability.
Alternate Names
activated RNA polymerase II transcription cofactor 4; activated RNA polymerase II transcriptional coactivator p15; p14; P15; PC4; positive cofactor 4; SUB1 homolog
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).