Rabbit anti-PDGFR alpha Recombinant Monoclonal Antibody [BLR078G]
Product Details
Specifications
Request Formulation Change Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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Immunogen was a recombinant protein representing the extracellular domain of human Platelet derived growth factor receptor alpha (residues 24-525, NP_006197.1).
Additional Product Information
Platelet derived growth factor receptor alpha is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGFR alpha and beta polypeptides. PDGFR alpha plays a role in organ development, wound healing, and tumor progression [taken from NCBI Entrez Gene (Gene ID: 5156)].
Alternate Names
Alpha platelet-derived growth factor receptor; alpha-type platelet-derived growth factor receptor; CD antigen CD140a; CD140 antigen-like family member A; CD140A; CD140a antigen; PDGFR2; PDGFR-2; PDGF-R-alpha; PDGFR-alpha; Platelet-derived growth factor alpha receptor; platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.