Rabbit anti-PTPN3 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A305-885A maps to a region between residue 175 and 225 of human Tyrosine-protein phosphatase non-receptor type 3 using the numbering given in entry P26045.2 (GeneID 5774).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to PTPN3 immobilized on solid support.
The epitope recognized by A305-885A-T maps to a region between residue 175 and 225 of human Tyrosine-protein phosphatase non-receptor type 3 using the numbering given in entry P26045.2 (GeneID 5774).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
PTPN3 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.PTPN3 contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. [taken from NCBI Entrez Gene (Gene ID: 5774)].
Alternate Names
cytoskeletal-associated protein tyrosine phosphatase; protein-tyrosine phosphatase H1; PTPH1; PTP-H1; tyrosine-protein phosphatase non-receptor type 3
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).