Rabbit anti-PYK2 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Protein tyrosine kinase 2 (PYK2) is a non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. PYK2 plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. It is required for normal macrophage polarization and migration towards sites of inflammation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14289].
Alternate Names
CADTK; CAKB; CAK-beta; calcium-dependent tyrosine kinase; calcium-regulated non-receptor proline-rich tyrosine kinase; cell adhesion kinase beta; FADK 2; FADK2; FAK2; focal adhesion kinase 2; PKB; proline-rich tyrosine kinase 2; protein kinase B; protein-tyrosine kinase 2-beta; PTK; PTK2B protein tyrosine kinase 2 beta; PYK2; RAFTK; related adhesion focal tyrosine kinase
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.