Rabbit anti-RIF1 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00203 maps to a region between residues 2425 and the C-terminus (residue 2472) of human Rap1 Interacting Factor 1 using the numbering given in entry NP_060621.3 (GeneID 55183). Antibody was affinity purified using an epitope specific to RIF1 immobilized on solid support.
The epitope recognized by IHC-00203-T maps to a region between residues 2425 and the C-terminus (residue 2472) of human Rap1 Interacting Factor 1 using the numbering given in entry NP_060621.3 (GeneID 55183).
Additional Product Information
RAP1 interacting factor (RIF1) localizes to dysfunctional telomeres and functions in the S-phase checkpoint. In response to double-stranded breaks (DSBs), RIF1 functions in the ATM and ATR mediated response to DNA damage. RIF1 foci formation in response to DNA damage is completely dependent on ATM.
Alternate Names
RAP1 interacting factor homolog; rap1-interacting factor 1 homolog; telomere-associated protein RIF1
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.