Rabbit anti-Senataxin Recombinant Monoclonal Antibody [BLR050F]
Product Details
Specifications
Immunogen was a peptide representing a region between residues 900 and 950 of human Senataxin using the numbering given in entry NP_055861.3 (Gene ID 23064).
Additional Product Information
Mutations in Senataxin result in the neurodegenerative disorders Ataxia-Oculomotor Apraxia 2 (AOA2) and amyotrophic lateral sclerosis (ALS4). Senataxin bears an RNA/DNA helicase domain suggesting a role in DNA and RNA processing and has recently been found to be involved in the DNA damage response.
Alternate Names
ALS4; amyotrophic lateral sclerosis 4 protein; AOA2; bA479K20.2; probable helicase senataxin; SCAR1; Sen1; SEN1 homolog; Senataxin
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.