Rabbit anti-SMARCA1/SNF2L IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00230 maps to a region between residue 1004 and 1054 of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (sucrose nonfermenting 2-like 1) using the numbering given in entry NP_003060.2 (GeneID 6594).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to SMARCA1/SNF2L immobilized on solid support.
The epitope recognized by IHC-00230-T maps to a region between residue 1004 and 1054 of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (sucrose nonfermenting 2-like 1) using the numbering given in entry NP_003060.2 (GeneID 6594).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. Member of this family have helicase and ATPase activities that alter chromatin structure to facilitate gene transcription. SMARCA1/SNF2L is a component of the human NURF (nucleosome remodeling factor) involved in the regulation of genes involved in neuronal development. SMARCA1/SNF2L is also a component of the heterodimeric complex CERF [CECR2(cat eye syndrome chromosome region, candidate 2)-containing remodeling factor].
Alternate Names
ATP-dependent helicase SMARCA1; global transcription activator homologous sequence; hSNF2L; ISWI; nucleosome-remodeling factor subunit SNF2L; NURF140; probable global transcription activator SNF2L1; SNF2L; SNF2L1; SNF2LB; SNF2-like 1; SNF2LT; sucrose nonfermenting 2-like protein 1; SWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1; SWI2
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.