Rabbit anti-SRP72 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A304-594A maps to a region between residue 621 to 671 of human Signal Recognition Particle 72kDa using the numbering given in entry NP_008878.3 (GeneID 6731).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to SRP72 immobilized on solid support.
The epitope recognized by A304-594A-T maps to a region between residue 621 to 671 of human Signal Recognition Particle 72kDa using the numbering given in entry NP_008878.3 (GeneID 6731).
Additional Product Information
Signal recognition particle subunit SRP72 is the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure [taken from NCBI Entrez Gene (Gene ID: 6731)].
Alternate Names
BMFF; BMFS1; epididymis luminal protein 103; HEL103; signal recognition particle 72 kDa protein; signal recognition particle 72kD; signal recognition particle 72kDa; signal recognition particle subunit SRP72; SRP72
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).