Rabbit anti-SUV39H1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A302-127A maps to a region between residue 25 and 75 of human suppressor of variegation 3-9 homolog 1 using the numbering given in entry NP_003164.1 (GeneID 6839).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to SUV39H1 immobilized on solid support.
The epitope recognized by A302-127A-T maps to a region between residue 25 and 75 of human suppressor of variegation 3-9 homolog 1 using the numbering given in entry NP_003164.1 (GeneID 6839).
Additional Product Information
SUV39H1 (suppressor of variegation 3-9 homolog 1) is a histone methyltransferase that specifically trimethylates histone H3 at lys 9. Trimethylation stimulates the binding of heterochromatin proteins (HPs) which leads to epigenetic transcriptional repression in heterochromatin regions.
Alternate Names
H3-K9-HMTase 1; histone H3-K9 methyltransferase 1; histone-lysine N-methyltransferase SUV39H1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; KMT1A; lysine N-methyltransferase 1A; MG44; position-effect variegation 3-9 homolog; Su(var)3-9 homolog 1; Suppressor of variegation 3-9 homolog 1; SUV39H
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.