Rabbit anti-Tankyrase 1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A302-398A-T maps to a region between residue 1 and 50 of human TRF1-interacting ankyrin-related ADP-ribose polymerase using the numbering given in entry NP_003738.2 (GeneID 8658).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to Tankyrase 1 immobilized on solid support.
The epitope recognized by A302-398A maps to a region between residue 1 and 50 of human TRF1-interacting ankyrin-related ADP-ribose polymerase using the numbering given in entry NP_003738.2 (GeneID 8658).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Tankyrase-1 is a poly(ADP-ribose) polymerase that localizes to telomeres via its interaction with TRF1. Tankyrase modifies and associates with multiple proteins and appears to be involved in the maintenance of telomere length, sister telomere association, mitotic spindle organization, and trafficking of glut4-containing vesicles.
Alternate Names
ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; PARP5A; PARP-5a; PARPL; pART5; poly ADP-ribose polymerase 5A; TANK1; tankyrase I; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; tankyrase-1; TIN1; TINF1; TNKS1; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; TRF1-interacting ankyrin-related ADP-ribose polymerase 1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.