Rabbit anti-THOP1 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A305-433A maps to a region between residue 25 to 75 of human Thimet oligopeptidase using the numbering given in entry P52888.2 (GeneID 7064).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to THOP1 immobilized on solid support.
The epitope recognized by A305-433A-T maps to a region between residue 25 to 75 of human Thimet oligopeptidase using the numbering given in entry P52888.2 (GeneID 7064).
Additional Product Information
Thimet oligopeptidase (THOP1) is a kininase that uses zinc as a cofactor. THOP1 cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. THOP1 also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides [taken from NCBI Entrez Gene (Gene ID: 7064)].
Alternate Names
endopeptidase 24.15; EP24.15; MEPD_HUMAN; MP78; thimet oligopeptidase; TOP
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).