Rabbit anti-TMED2 Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by A305-467A maps to a region between residue 50 to 100 of human Transmembrane emp24 domain-containing protein 2 using the numbering given in entry Q15363.1 (GeneID 10959).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to TMED2 immobilized on solid support.
The epitope recognized by A305-467A-T maps to a region between residue 50 to 100 of human Transmembrane emp24 domain-containing protein 2 using the numbering given in entry Q15363.1 (GeneID 10959).
Additional Product Information
TMED2 is involved in vesicular protein trafficking. TMED2 mainly functions in the early secretory pathway but also in post-Golgi membranes. It is thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15363].
Alternate Names
coated vesicle membrane protein; membrane protein p24A; p24; p24 family protein beta-1; P24A; p24b1; p24beta1; RNP24; transmembrane emp24 domain trafficking protein 2; transmembrane emp24 domain-containing protein 2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).