Rabbit anti-TORC2 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00564 maps to a region between residues 300 and 350 of human Transducer of Regulated cAMP Responsive Element-Binding Protein (CREB) 2 using the numbering given in entry NP_859066.1 (GeneID 200186).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to TORC2 immobilized on solid support.
The epitope recognized by IHC-00564-T maps to a region between residues 300 and 350 of human Transducer of Regulated cAMP Responsive Element-Binding Protein (CREB) 2 using the numbering given in entry NP_859066.1 (GeneID 200186).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
TORC2 (transducer of regulated CREB activity 2) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC1 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. TORC2 has been found to be pivotal to the process of gluconeogenesis.
Alternate Names
CREB-regulated transcription coactivator 2; TORC2; TORC-2; Transducer of CREB protein 2; transducer of regulated cAMP response element-binding protein (CREB) 2; Transducer of regulated cAMP response element-binding protein 2
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.