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Rabbit anti-UBR2 Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
UBR2
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1705 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Mouse, Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to UBR2 immobilized on solid support.

The epitope recognized by A305-416A maps to a region between residue 1705 to 1755 of human E3 ubiquitin-protein ligase UBR2 using the numbering given in entry Q8IWV8.1 (GeneID 23304).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to UBR2 immobilized on solid support.

The epitope recognized by A305-416A-T maps to a region between residue 1705 to 1755 of human E3 ubiquitin-protein ligase UBR2 using the numbering given in entry Q8IWV8.1 (GeneID 23304).
Country of Origin
USA

Additional Product Information

UBR2 is an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation [taken from NCBI Entrez Gene (Gene ID: 23304)].

23304
UBR2
ubiquitin protein ligase E3 component n-recognin 2
Q8IWV8
E3 ubiquitin-protein ligase UBR2

Alternate Names

bA49A4.1; C6orf133; dJ242G1.1; dJ392M17.3; E3 ubiquitin-protein ligase UBR2; N-recognin-2; RING-type E3 ubiquitin transferase UBR2; ubiquitin-protein ligase E3-alpha-2; ubiquitin-protein ligase E3-alpha-II

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.