Rabbit anti-XPA IHC Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Mutations in XPA (xeroderma pigmentosum group A-complementing protein) are the cause of xeroderma pigmentosum A (XP-A), an autosomal recessive disease that is mainly characterized by a susceptibility to UV-induced skin cancer and in some cases neurological abnormalities. XPA is one of seven XP complementation groups that have been identified. The XP complementation groups represent genes critical to the nucleotide excision repair (NER) pathway. XPA is thought to function in the recognition of DNA damage and as a processivity factor for XPF and XPG.
Alternate Names
DNA repair protein complementing XP-A cells; xeroderma pigmentosum group A-complementing protein; xeroderma pigmentosum, complementation group A; XP1; XPAC
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.